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More robust CYP3A4 inhibitors such as ketoconazole or itraconazole may very well be expected to own bigger effects than witnessed with saquinavir. A setting up dose of 25 mg of VIAGRA really should be thought of in people having erythromycin or robust CYP3A4 inhibitors (which include saquinavir, ketoconazole, itraconazole) [see DOSAGE AND ADMINISTR